PAR4-AP

Number: P1000011
Name: PAR4-AP
Sequence: Ala-Tyr-Pro-Gly-Lys-Phe-NH2 (AYPGKF-NH2)
Description: Ala-Tyr-Pro-Gly-Lys-Phe-NH2 (AYPGKF-NH2) is a selective proteinase-activated receptor 4 (PAR4) specific agonist peptide
Ala-Tyr-Pro-Gly-Lys-Phe-NH2 (AYPGKF-NH2) is a selective proteinase-activated receptor 4 (PAR4) specific agonist peptide, which may be used for probing PAR4 signaling in culture systems and in platelets. AYPGKF stimulates platelet aggregation in vitro (EC50 =15 uM). Human platelets with the PAR4 agonist AYPGKF stimulates the production of thromboxane. The thrombin-induced release of endostatin from rat platelets is mediated by the PAR4 agonist AYPGKF and in contrast, the PAR4 antagonist trans-cinnamoyl- YPGKF-NH2 (Product No. C 7363) blocks endostatin release and platelet aggregation.

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PAR4-AP - Biopeptek

PAR4-AP

Number: P1000011
Name: PAR4-AP
Sequence: Ala-Tyr-Pro-Gly-Lys-Phe-NH2 (AYPGKF-NH2)
Description: Ala-Tyr-Pro-Gly-Lys-Phe-NH2 (AYPGKF-NH2) is a selective proteinase-activated receptor 4 (PAR4) specific agonist peptide
Ala-Tyr-Pro-Gly-Lys-Phe-NH2 (AYPGKF-NH2) is a selective proteinase-activated receptor 4 (PAR4) specific agonist peptide, which may be used for probing PAR4 signaling in culture systems and in platelets. AYPGKF stimulates platelet aggregation in vitro (EC50 =15 uM). Human platelets with the PAR4 agonist AYPGKF stimulates the production of thromboxane. The thrombin-induced release of endostatin from rat platelets is mediated by the PAR4 agonist AYPGKF and in contrast, the PAR4 antagonist trans-cinnamoyl- YPGKF-NH2 (Product No. C 7363) blocks endostatin release and platelet aggregation.

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